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KMID : 0903519980410080613
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Journal of the Korean Society of Agricultural Chemistry and Biotechnology
1998 Volume.41 No. 8 p.613 ~ p.615
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Existence of Thermally Stable Thrombin Inhibitors in Soybean Paste , Doenjang
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Hwang, Woo Ik
Jung, Jin/Oh, Nam Soon/Kim, Dong Chung/In, Man Jin
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Abstract
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Antithrombotic function of doenjang was investigated using thoroughly desalted aqueous extract. In the presence of the extract, thrombin suffered loss of its fibrin-clotting activity, whose extent increased in a dose-dependent manner. The active substance involved in thrombin inhibition showed a high thermal stability. Results of Sephadex G-25 permeation chromatography indicated that there were at least two soluble thrombin inhibitors in doenjang with different molecular sizes.
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KEYWORD
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